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5-APDB has been shown to inhibit serotonin, dopamine, and non stimulant.




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5-MAPDB is a chemical compound which might be an entactogenic drug. It is structurally related to drugs like 5-APDB and 5-MAPB, which have similar effects to MDMA and have been used as recreational drugs.

This paper reports analytical properties of five substituted phenethylamine derivatives seized from a clandestine laboratory. These five derivatives include 5-(2-methylaminopropyl)-2,3-dihydrobenzofuran (5-MAPDB, 1), 5-(2-aminoethyl)-2,3-dihydrobenzofuran (5-AEDB, 2), N,2-dimethyl-3-(3,4-methylenedioxyphenyl)propan-1-amine (MDMA methylene homolog, 3), 6-bromo-3,4-methylenedioxymethamphetamine (6-Br-MDMA, 4), and 1-(benzofuran-5-yl)-N-(2-methoxybenzyl)propan-2-amine (5-APB-NBOMe, 5). These compounds were identified by liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS), gas chromatography-mass spectrometry (GC-MS), and nuclear magnetic resonance spectroscopy (NMR). No analytical properties about compounds 1-4 have appeared until now, making this the first report on these compounds.

5-mapdb hcl with an iupac name of (1-(2,3-dihydrobenzofuran-5-yl)-n-methylpropan-2-amine) and a molecular weight of 191.48 is a new research chemical. the cas number for 5-mapdb hcl is 1354631-78-9 and the chemical formula is c12h17no. since the chemical is new on the market, there is no research available at this time. the analogue to c12h17no is 5-eapb, so we can use this research chemical as an example.

5-eapb has an iupac name of 1-(1-benzofuran-5-yl)-n-ethyl-2-propanamine a molecular formula of c13h17no and an average mass of 203.280.

research on 5-eapb was conducted by acd/labs’ and chemaxon. acd/labs showed 2 #h bond acceptors, 1 #h bond donor, 4 #freely rotating bonds, index of refraction at 1.554 with a surface tension of 36.5±3.0 dyne/cm, a flash point of 133.2±20.4 °c and a boiling point of 296.6±15.0 °c at 760 mmhg.

chemaxon published a topology analysis, which revealed an atom count of 32, bond count of 33, cyclomatic number of 2, chain atom count of 6, chain bond count of 6, asymmetric atom count of 1, and rotatable bond count of 4. under geometry, the report revealed a dreiding energy equal to 42.55 kcal/mol with a volume equal to 203.78 å3, a minimal projection area equal to 30.80 å2 and maximum projection area equal to 69.85 å2.

5-mapdb hcl and 5-eapb are only intended for scientific and forensic research and is not for human consumption.



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