AB-PINACA is a synthetic cannabinoid usually sold as a herbal smoking mixture designed to mimic THC, the active chemical of cannabAis. Synthetic cannabinoids are classed as ‘New Psychoactive Substances’ (NPS) which are unregulated substances that have become newly available on the market as an alternative to illegal drugs. As a reaction to prohibition, synthetic cannabinoid producers change the compounds found in designer drugs and create new generations of synthetic drugs, such as AB-PINACA. As a result, accidental overdose and severe psychiatric complications may be more likely to occur because the type and amount of active compound may vary considerably from batch to batch. Other effects may include agitation, rapid heart rate, confusion, dizziness and nausea.
AB–PINACA is a compound that was first identified as a component of synthetic cannabis products in Japan in 2012. It was originally developed by Pfizer in 2009 as an analgesic medication.
AB-PINACA (Item No. 14038) is an analytical reference material categorized as a cannabinoid.1 AB-PINACA is regulated as a Schedule I compound in the United States. This product is intended for research and forensic applications.
This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.
AB-PINACA is a synthetic cannabinoid similar to the natural cannabinoid Tetrahydrocannabinol (THC) , which shares many of the same chemical properties and is currently enjoying just as much attention from the global research community.
globalresearchemvendor.com – has recently made it possible to purchase AB-PINACA, which can be used as a viable research alternative to much sought-after, but largely illegal natural cannabinoids like THC or dronabinol.
globalresearchemvendor.com provides you with the amazing possibility to buy AB-PINACA in a very pure form from a certified vendor, so that you can make your scientific research with the best available chemical materials.
The chemical formula of AB-PINACA indicated that the effects of this chemical compound might be very similar of THC – the active substance of the cannabis plant . Its pharmacology can provide strong interaction with CB1 and CB2 receptors and a possible role as a cannabinoid agonist, which could give the research chemical antidepressant and analgesic properties.
Please note that AB-PINACA can be studied only under optimal laboratory conditions and that in vivo research involving live organisms is not allowed. AB-PINACA can be safely stored for up to 2 years on room temperature
Synthetic cannabinoids (SC), are a novel class of designer drugs which emerged as a drug of abuse in the late 2000’s. We report a case series of 6 patients who may have smoked a synthetic cannabinoid product in a remote wilderness setting. They presented with varying degrees of altered mental status, agitation, and seizures. Two were confirmed to have AB-PINACA, ADB-PINACA and their respective pentanoic acid metabolites in biological specimens via liquid chromatography time-of-flight mass spectrometry (LC-TOF/MS). Both compounds had DEA Schedule I classification at the time of case presentation, and 22 SCs are currently temporary or permanent DEA Schedule I. More than 150 SCs are known to date, and new compounds are appearing at a rapid rate on darknet and surface web e-commerce websites, marketed as “research chemicals” or “legal highs.” The scale and rapidity of SC evolution make legal control and analytical detection difficult. Nontargeted testing with liquid chromatography high resolution mass spectrometry (LC-HRMS), examining both parent compounds and metabolites, is the ideal method for novel SC identification and confirmation. Due to full agonism at the cannabinoid receptors CB1 and CB2, clinical effects are more severe than marijuana, which is a partial cannabinoid receptor agonist. They include agitated delirium, lethargy and coma, seizures, tachycardia, hypertension, and hallucinations, among other findings. Treatment is primarily symptomatic and aimed at airway protection and control of agitation and seizures. SCs do not appear to be abating anytime soon and require the cooperation of law enforcement, analytical scientists, and clinicians to adequately control.
UB – AKB48 which in the chemical nomenclature is also known as F5-APINICA is an indazole- constituted synthetic designer cannabinoid and it is also considered to be a strong agonist for receptors like CB1 and CB2. We supply in bulk and small order starting as low as 25 grams .
NM-2201 (also known as CBL-2201) is an indole-based synthetic cannabinoid that is presumably a full agonist and unselectively binds to CB1 and CB2 receptors with low nanomolar affinity, the potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, respectively. Little to no research data available on this chemical makes it impossible to describe it’s properties in detail.
NM-2201 is a synthetic cannabinoid is similar in structure to AM-2201, differing by an ester linking the 3’ position to the naphthyl group. This drug was discovered by Alexandros Makriyannis from Northeastern University.The physiological and toxicological properties of this compound are not currently known.This product is intended for forensic and research applications.
The present study aims to recommend appropriate marker metabolites for documenting SDB-006 consumption by investigating its metabolism in human hepatocytes. For metabolite profiling, 10 µM of SDB-006 was incubated in human hepatocytes for 3 h. Metabolite identification in hepatocyte samples was accomplished with high-resolution mass spectrometry via information-dependent data acquisition. Results revealed that SDB-006 was highly metabolized in human hepatocytes.